Dhaka, Jan 21 (V7N): Infections account for 20-40% of newborn deaths in Bangladesh, according to two major clinical trials aimed at improving the management of potential severe bacterial infections (PSBI) in infants under two months old.

The findings were presented at an event held at Radisson Blu Water Garden Hotel in Dhaka on Monday, organized by the Ministry of Health and Family Welfare and the Projahnmo Research Foundation (PRF). The trials explored innovative, low-cost treatment methods tailored for resource-limited settings.

Professor Dr. Md. Sayedur Rahman, special assistant to the chief adviser, highlighted the global significance of this issue, stating, “Infections in infants under two months are a leading cause of death for children under five, particularly in low- and middle-income countries. Globally, 60-70% of under-five deaths occur within the first two months of life.”

Key Findings from the Clinical Trials:

  • Severe bacterial infections affect 8-10% of infants within their first two months.
  • Low-cost antibiotics, such as amoxicillin and gentamicin, were found effective in treating these infections.
  • For low-risk infants, outpatient or home-based care proved to be safe and reduced the need for hospitalization.
  • Moderate-risk infants responding well to 48-hour injectable antibiotics benefited from early discharge with oral antibiotics for home care.

The trials, funded by the Bill and Melinda Gates Foundation, were conducted across six countries: Bangladesh, Ethiopia, India, Nigeria, Pakistan, and Tanzania. The findings emphasized reducing unnecessary hospital admissions, minimizing healthcare costs, and improving outcomes for families.

Implications for Healthcare in Bangladesh

The study's findings present a new approach to managing newborn infections in resource-limited settings, offering safer, cost-effective, and more accessible care options.

“These evidence-based practices are essential for enhancing newborn healthcare and tackling one of the most critical global health challenges,” said Professor Dr. Md. Abu Jafar, Director General of the Directorate General of Health Services, who attended the event as the chief guest.

The presentation brought together policymakers, senior pediatricians, and stakeholders to discuss the integration of these practices across Bangladesh and other low-income countries, with the potential to save countless newborn lives.

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